SCHEMBL9835741

SCHEMBL9835741

C=C(CC)C(OC(=O)Nc1ccc(Cl)cc1)C(=O)OCC(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
KIT P10721 1/20 0.43
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
UTS2R Q9UKP6 3/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835172 0.88 MAPT (0.52) MAPTL3MBTL1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL9835915 0.77 MAPT (0.46) MAPTL3MBTL1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL9837783 0.77 TSHR (0.41) MAPTL3MBTL1KMT2ASMN1; SMN2LMNA
SCHEMBL9837472 0.76 MAPT (0.48) MAPTL3MBTL1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL9835708 0.75 LMNA (0.52) L3MBTL1ALDH1A1SMN1; SMN2LMNATSHR
SCHEMBL9836991 0.75 MAPT (0.46) MAPTL3MBTL1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL9833817 0.75 HPGD (0.44) MAPTALDH1A1KMT2ASMN1; SMN2HPGD
SCHEMBL9834808 0.74 MAPT (0.54) MAPTL3MBTL1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL9836424 0.73 MAPT (0.52) MAPTL3MBTL1ALDH1A1KMT2APOLB
SCHEMBL27314996 0.73 MAPT (0.44) MAPTL3MBTL1SMN1; SMN2HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed