SCHEMBL9837527

SCHEMBL9837527

O=C1C=CC(=O)N1c1ccc(O)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.55
NPSR1 Q6W5P4 5/20 0.48
HSP90AA1 P07900 4/20 0.48
PKM P14618 3/20 0.48
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
HSD17B10 Q99714 1/20 0.45
TLR9 Q9NR96 3/20 0.43
ALDH1A1 P00352 4/20 0.43
HTT P42858 3/20 0.43
MITF O75030 1/20 0.43
ATM Q13315 1/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
MAPT P10636 2/20 0.42
CCR6 P51684 2/20 0.42
APOBEC3G Q9HC16 2/20 0.42
RAB9A P51151 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075617 0.80 MGLL (0.59) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL30464215 0.80 MGLL (0.59) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL10587456 0.78 MGLL (0.57) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL26667212 0.78 MGLL (0.57) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL23388366 0.77 MGLL (0.55) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL29485051 0.77 MGLL (0.55) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL9838829 0.77 MGLL (0.55) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL3869199 0.77 ESR1 (0.62) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL30474623 0.77 ESR1 (0.62) MGLLNPSR1HSP90AA1PKMMAPK1
SCHEMBL30645221 0.77 MGLL (0.58) MGLLNPSR1HSP90AA1PKMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1692017-A Flexible metal laminate and heat-resistant adhesive composition TOMOEGAWA PAPER CO LTD (JP) 2005-11-02 CN disclosed
US-5075453-A Process for producing aryloxy-substituted phosphazene derivatives NIPPON SODA CO., LTD. (JP) 1991-12-24 US disclosed
US-4855389-A Process for producing phosphonitrile oligomers containing maleimidophenoxy group SHIN NISSO KAKO CO., LTD. (JP) 1989-08-08 US disclosed