Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837599 | 0.91 | SHMT2 (0.40) | SHMT2ALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL9687121 | 0.75 | GRIN1 (0.34) | ALDH1A1TDP1KMT2AMAPTKDM4E | |
| SCHEMBL11104285 | 0.69 | PPOX (0.39) | ALDH1A1KMT2AL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL10413738 | 0.66 | SHMT2 (0.36) | SHMT2ALDH1A1HPGDKDM4E | |
| SCHEMBL9839357 | 0.66 | SHMT2 (0.39) | SHMT2ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL8355924 | 0.64 | SHMT2 (0.45) | SHMT2ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL9478574 | 0.64 | TP53 (0.37) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9478581 | 0.64 | TP53 (0.37) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL11571205 | 0.63 | KMT2A (0.52) | ALDH1A1HPGDPOLBKMT2AL3MBTL1 | |
| SCHEMBL9478926 | 0.63 | SMN1; SMN2 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230874-B1 | BENZOTHIAZOLYLAZOLIDINES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4898948-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4828605-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-09 | — | — | US | disclosed |
| US-4786310-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0230874-A1 | Benzothiazolylazolidines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-05 | — | — | EP | disclosed |