SCHEMBL9838012

SCHEMBL9838012

O=C1C=CC(=O)N1c1cccc(I)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 1.00
FAAH O00519 7/20 1.00
HSP90AA1 P07900 4/20 0.60
ALDH1A1 P00352 1/20 0.58
PKM P14618 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
HPN P05981 1/20 0.53
MPI P34949 1/20 0.44
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94730 0.84 MGLL (1.00) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL1838889 0.84 MGLL (1.00) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL30958998 0.82 MGLL (0.95) MGLLFAAHHSP90AA1ALDH1A1PKM
Water SCHEMBL5808596 0.80 MGLL (0.91) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL3179484 0.78 MGLL (0.88) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL11754744 0.78 MGLL (0.63) MGLLFAAHHSP90AA1PKM
SCHEMBL2847212 0.77 MGLL (1.00) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL24452764 0.75 MGLL (0.72) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL3916468 0.75 MGLL (0.72) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL12462984 0.75 MGLL (1.00) MGLLFAAHHSP90AA1ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112358479-A Synthesis method of pyrrolo [3,4-c ] quinoline-1, 3-diketone compound 西北师范大学 2021-02-12 CN disclosed
US-4994557-A Radiohalogenated half-antibodies and maleimide intermediate therefor PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1991-02-19 US disclosed