SCHEMBL9838121

SCHEMBL9838121

CC(C)(COCc1ccc(F)c(Oc2ccc(F)cc2)c1)c1ccc(OC(F)F)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
ALOX12 P18054 1/20 0.34
KMT2A Q03164 1/20 0.34
RORC P51449 1/20 0.32
PPARG P37231 2/20 0.32
POLB P06746 1/20 0.32
PPARA Q07869 1/20 0.32
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
CNR2 P34972 1/20 0.31
RXRA P19793 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
PER2 O15055 1/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558277 0.92 MRGPRX4 (0.34) LMNAPPARGPOLBPPARAMRGPRX4
SCHEMBL9558421 0.87 HTR2A (0.41) PPARGPPARAGRIN1GRIN2BKCNH2
SCHEMBL9558013 0.87 RAB9A (0.38) LMNAMAPTKMT2APOLBSMN1; SMN2
SCHEMBL9557935 0.87 SLC6A4 (0.37) LMNAMAPTPPARGPPARAL3MBTL1
SCHEMBL10837314 0.86 HTR2A (0.38) LMNAMEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL9559005 0.85 SLC6A4 (0.38) PPARGPPARAMRGPRX4
SCHEMBL9558493 0.85 CACNA1C (0.44) LMNAHTTALDH1A1MAPTPPARG
SCHEMBL9558357 0.85 PPARA (0.32) PPARGPPARACACNA1CKCNH2
SCHEMBL9798911 0.83 FFAR4 (0.38) MEN1MAPTKMT2AKCNH2
SCHEMBL9558334 0.83 PPARG (0.39) LMNAPPARGPPARASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed