Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.77 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.77 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.63 |
| ▸ | PARP1 | P09874 | 2/20 | 0.63 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.63 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NMT1 | P30419 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838285 | 1.00 | LPAR2 (0.77) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL441804 | 0.88 | LPAR2 (1.00) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL441805 | 0.88 | LPAR2 (1.00) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL1552033 | 0.88 | LPAR2 (1.00) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| Iodide SCHEMBL1552156 | 0.86 | LPAR2 (0.96) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL18486004 | 0.83 | MMP1 (0.71) | MAPTTRPV1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17179659 | 0.83 | MMP1 (0.71) | MAPTTRPV1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11758320 | 0.82 | LPAR2 (0.59) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL6545766 | 0.81 | LPAR2 (0.80) | LPAR2LPAR1CREBBPALDH1A1MAPT | |
| SCHEMBL7457467 | 0.81 | LPAR2 (0.80) | LPAR2LPAR1CREBBPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994557-A | Radiohalogenated half-antibodies and maleimide intermediate therefor | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-02-19 | — | — | US | disclosed |