SCHEMBL9838339

SCHEMBL9838339

CCc1ncnc(NC(C)c2ccc(S(=O)(=O)C(F)F)cc2)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
EGFR P00533 10/20 0.36
TAAR1 Q96RJ0 1/20 0.35
PIK3CA P42336 2/20 0.35
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
GALR3 O60755 1/20 0.34
NR2F2 P24468 1/20 0.34
P2RX3 P56373 1/20 0.34
PRKDC P78527 1/20 0.32
PRCP P42785 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9838083 0.87 EGFR (0.47) EGFRPIK3CAGALR3NR2F2P2RX3
SCHEMBL9838401 0.80 CNR1 (0.34) EGFRCNR1CNR2GALR3NR2F2
SCHEMBL9729823 0.79 EGFR (0.39) ALDH1A1EGFRCNR1CNR2GALR3
SCHEMBL9836824 0.79 SMN1; SMN2 (0.36) ALDH1A1EGFRCNR1CNR2GALR3
SCHEMBL17085318 0.79 GALR3 (0.54) EGFRGALR3NR2F2LMNA
SCHEMBL9838456 0.78 GALR3 (0.38) EGFRCNR1CNR2GALR3NR2F2
SCHEMBL8304355 0.78 GALR3 (0.38) EGFRCNR1CNR2GALR3NR2F2
SCHEMBL9838384 0.78 GALR3 (0.36) EGFRCNR1CNR2GALR3NR2F2
SCHEMBL8024904 0.77 RORC (0.37) ALDH1A1EGFRTAAR1PIK3CACNR1
SCHEMBL9729028 0.74 EGFR (0.41) EGFRCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424125-A2 Aralkylamine derivatives, preparation method thereof and fungicides containing the same UBE INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed