Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728955 | 0.85 | EGFR (0.43) | EGFRPDE4AKRASSOS1CNR1 | |
| SCHEMBL9729823 | 0.85 | EGFR (0.39) | EGFRCRHR1KRASSOS1CNR1 | |
| SCHEMBL8014129 | 0.80 | EGFR (0.43) | EGFRKRASSOS1ERBB2 | |
| SCHEMBL9193841 | 0.77 | CRHR1 (0.39) | EGFRCRHR1 | |
| SCHEMBL8024922 | 0.77 | EGFR (0.42) | EGFRKRASSOS1CNR1CNR2 | |
| SCHEMBL9279868 | 0.77 | EGFR (0.38) | EGFRPDE4AKRASSOS1CNR1 | |
| SCHEMBL8756068 | 0.77 | TPH1 (0.40) | EGFRCRHR1KRASSOS1 | |
| SCHEMBL9836824 | 0.76 | SMN1; SMN2 (0.36) | EGFRCRHR1CNR1CNR2 | |
| SCHEMBL17085318 | 0.76 | GALR3 (0.54) | EGFRKRASSOS1 | |
| SCHEMBL16997376 | 0.76 | EGFR (0.41) | EGFRKRASSOS1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | claimed |