Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.64 |
| ▸ | RELA | Q04206 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | PKM | P14618 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266928 | 0.88 | KDM4E (0.63) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL12967444 | 0.87 | SMN1; SMN2 (0.62) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL28265575 | 0.85 | KDM4E (0.60) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL28201482 | 0.84 | KDM4E (0.67) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL697049 | 0.84 | KDM4E (0.71) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL24906049 | 0.83 | KDM4E (0.62) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL21115735 | 0.83 | KDM4E (0.62) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL4905432 | 0.81 | RAB9A (0.64) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL21351047 | 0.81 | RAB9A (0.61) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL3501001 | 0.80 | KDM4E (1.00) | KDM4ERAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180590-A | A method of Benzoheterocyclic compounds are quickly prepared using physical grinding method under room temperature solvent-free | 福建医科大学 | 2019-01-11 | — | — | CN | disclosed |
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC | 2011-03-31 | — | — | US | disclosed |
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | MAP3K20, MAP3K1, PDPK1 | KDM4E 770/4885RAB9A 2801/4885NFKB1 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.