Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.63 |
| ▸ | RELA | Q04206 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697049 | 0.84 | KDM4E (0.71) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL9838440 | 0.84 | KDM4E (0.67) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL28266928 | 0.81 | KDM4E (0.63) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL4905432 | 0.81 | RAB9A (0.64) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL24906049 | 0.80 | KDM4E (0.62) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL3501001 | 0.80 | KDM4E (1.00) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL21115735 | 0.80 | KDM4E (0.62) | KDM4ERAB9ANFKB1NFKB2RELA | |
| Methane SCHEMBL11880803 | 0.79 | KDM4E (0.97) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL28265575 | 0.79 | KDM4E (0.60) | KDM4ERAB9ANFKB1NFKB2RELA | |
| SCHEMBL3187010 | 0.79 | KDM4E (0.68) | KDM4ERAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |