SCHEMBL9838466

SCHEMBL9838466

CCOC(=O)C(C#N)C(C=C(c1ccc(N(CC)CC)cc1)c1ccc(N(CC)CC)cc1)C=C(c1ccc(N(CC)CC)cc1)c1ccc(N(CC)CC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.42
ALDH1A1 P00352 10/20 0.42
MEN1 O00255 8/20 0.42
KMT2A Q03164 8/20 0.42
POLB P06746 7/20 0.42
L3MBTL1 Q9Y468 6/20 0.42
MAPK1 P28482 5/20 0.42
LMNA P02545 3/20 0.42
USP2 O75604 2/20 0.42
RECQL P46063 2/20 0.42
BLM P54132 1/20 0.42
NPY1R P25929 1/20 0.39
NPY2R P49146 1/20 0.39
TLR9 Q9NR96 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 3/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9838406 0.91 ESRRG (0.37) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9839736 0.89 ALDH1A1 (0.42) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL10426771 0.89 EGFR (0.39) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9840319 0.79 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9838517 0.73 MAPT (0.47) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9839532 0.69 CNR2 (0.48) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL4694984 0.69 MAPT (0.45) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL4694986 0.69 MAPT (0.45) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL9749967 0.69 ALDH1A1 (0.46) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL65692 0.69 CA12 (0.61) MAPTALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057154-A Colorfastness, stability RICOH COMPANY, LTD. (JP) 1991-10-15 US disclosed
US-4939117-A Leuco dyes and recording material employing the same RICOH COMPANY, LTD. (JP) 1990-07-03 US disclosed