Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363682 | 0.76 | TSHR (0.34) | TSHRTDP1 | |
| SCHEMBL181531 | 0.73 | TSHR (0.35) | MAPTTSHRLMNARGS12TDP1 | |
| SCHEMBL1981591 | 0.67 | OPRL1 (0.46) | MEN1KMT2AMAPTALOX12TSHR | |
| SCHEMBL3503449 | 0.67 | OPRL1 (0.49) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL2161809 | 0.65 | OPRL1 (0.51) | KMT2ATSHRLMNA | |
| SCHEMBL1809020 | 0.64 | TSHR (0.38) | TSHRRGS12TDP1 | |
| SCHEMBL6632635 | 0.64 | TSHR (0.38) | TSHRRGS12TDP1 | |
| SCHEMBL7534039 | 0.63 | BRD4 (0.33) | TSHRTDP1 | |
| SCHEMBL11422629 | 0.63 | ALDH1A1 (0.47) | MAPTTSHRTDP1 | |
| SCHEMBL16341346 | 0.63 | OPRL1 (0.37) | MEN1KMT2AMAPTALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |