Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PTAFR | P25105 | 19/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512188 | 0.92 | PTAFR (0.52) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9837230 | 0.91 | PTAFR (0.62) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9838502 | 0.80 | PTAFR (0.59) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9838409 | 0.77 | PTAFR (0.53) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9045091 | 0.76 | OPRK1 (0.61) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9837220 | 0.76 | PTAFR (0.57) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10462569 | 0.74 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10513238 | 0.72 | PTAFR (0.50) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10469718 | 0.72 | PTAFR (0.88) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL10869413 | 0.71 | OPRK1 (0.90) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | claimed |
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |