Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177398 | 0.97 | CYP2D6 (0.42) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL17512704 | 0.82 | S1PR1 (0.43) | EPHX1EPHX2S1PR1S1PR5GAA | |
| SCHEMBL9185202 | 0.81 | KMT2A (0.46) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9185084 | 0.81 | CTSK (0.40) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| Ammonia Solution, Strong SCHEMBL9182347 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4466104 | 0.80 | CHRM3 (0.43) | ALDH1A1S1PR1S1PR5 | |
| SCHEMBL4481788 | 0.78 | ATM (0.40) | ALDH1A1MEN1KMT2AKDM4EEPHX1 | |
| SCHEMBL4481787 | 0.78 | ATM (0.40) | ALDH1A1MEN1KMT2AKDM4EEPHX1 | |
| SCHEMBL20811432 | 0.77 | MEN1 (0.40) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL21737963 | 0.75 | KMT2A (0.50) | ALDH1A1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002526-A1 | AZABICYCLO QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1991-03-07 | — | — | WO | disclosed |