Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481788 | 1.00 | ATM (0.40) | ATMKDM4EBACE1SCN5ASCN9A | |
| SCHEMBL9177398 | 0.80 | CYP2D6 (0.42) | KDM4EMEN1KMT2AALDH1A1S1PR1 | |
| SCHEMBL17512704 | 0.78 | S1PR1 (0.43) | S1PR1S1PR5EPHX1EPHX2 | |
| SCHEMBL9838655 | 0.78 | ALDH1A1 (0.42) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9185084 | 0.76 | CTSK (0.40) | KDM4EBACE1MEN1KMT2AALDH1A1 | |
| SCHEMBL4466104 | 0.75 | CHRM3 (0.43) | ALDH1A1S1PR1S1PR5ARG1ARG2 | |
| SCHEMBL9185202 | 0.74 | KMT2A (0.46) | KDM4EMEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9182347 | 0.73 | KMT2A (0.45) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18428237 | 0.70 | SIGMAR1 (0.45) | KDM4EMEN1KMT2AALDH1A1S1PR1 | |
| SCHEMBL4200481 | 0.70 | GRIN2B (0.43) | ATMBACE1SCN5ASCN9AAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592359-B2 | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-09-22 | — | — | US | disclosed |
| US-20070287732-A1 | Substituted Azabicyclo Hexane Derivatives as Muscarinic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287732-A1 | Substituted Azabicyclo Hexane Derivatives as Muscarinic Receptor Antagonists | CHRM5, CHRM3, CHRM2 | ATM 3937/4885KDM4E 2238/4885BACE1 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.