SCHEMBL9839005

SCHEMBL9839005

[CH2]c1ccc(OCF)nc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9840564 0.83 APP (0.40) L3MBTL1MAPT
SCHEMBL130177 0.78 MAPT (0.52) MAPT
SCHEMBL9092192 0.78 L3MBTL1 (0.56) L3MBTL1MAPT
SCHEMBL9839025 0.75 HRH3 (0.31) MAPT
SCHEMBL9839954 0.75 HRH3 (0.31) MAPT
SCHEMBL17562257 0.74 CCR1 (0.44) MAPT
SCHEMBL20886038 0.74 KDM4E (0.52) L3MBTL1MAPT
SCHEMBL125509 0.73
SCHEMBL9839858 0.72 L3MBTL1 (0.32) L3MBTL1
SCHEMBL9838960 0.72 DAO (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212600-B1 NITROMETHYLENE DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 1991-11-27 EP disclosed
US-4812454-A Nitromethylene derivatives and their use as insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-03-14 US disclosed
US-4772620-A MITICIDES, PARASITICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-09-20 US disclosed
EP-0212600-A2 Nitromethylene derivatives NIHON BAYER AGROCHEM K.K. (JP) 1987-03-04 EP disclosed