Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839005 | 0.83 | L3MBTL1 (0.33) | MAPTL3MBTL1 | |
| SCHEMBL9839025 | 0.80 | HRH3 (0.31) | MAPTHRH3 | |
| SCHEMBL9839954 | 0.80 | HRH3 (0.31) | MAPTHRH3 | |
| SCHEMBL30461568 | 0.76 | KDM4E (0.49) | APPMAPTSNCAPIK3CDPIK3CA | |
| SCHEMBL120011 | 0.76 | APP (0.40) | APPMAPTSNCASLC18A3 | |
| SCHEMBL13420116 | 0.76 | APP (0.40) | APPMAPTSNCASLC18A3ELOVL1 | |
| SCHEMBL16466281 | 0.76 | APP (0.40) | APPMAPTSNCA | |
| SCHEMBL16943516 | 0.76 | KDM4E (0.49) | APPMAPTSNCAPIK3CDPIK3CA | |
| SCHEMBL15489125 | 0.76 | APP (0.43) | APPMAPTSNCA | |
| SCHEMBL28627900 | 0.76 | CHRNB2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212600-B1 | NITROMETHYLENE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4812454-A | Nitromethylene derivatives and their use as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4772620-A | MITICIDES, PARASITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0212600-A2 | Nitromethylene derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1987-03-04 | — | — | EP | disclosed |