Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477973 | 0.85 | MEN1 (0.56) | ADORA3MAPK14KDM4EMEN1KMT2A | |
| SCHEMBL9312281 | 0.85 | NQO2 (0.51) | ADORA3MAPK14MEN1KMT2ACYP26A1 | |
| SCHEMBL9312304 | 0.84 | GSK3B (0.53) | ADORA3MEN1KMT2ACYP26A1CYP3A4 | |
| SCHEMBL9313806 | 0.83 | ADORA3 (0.48) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL9840703 | 0.82 | MAPK14 (0.45) | ADORA3MAPK14MEN1KMT2ACYP26A1 | |
| SCHEMBL10478091 | 0.82 | TRPV1 (0.52) | RORCMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10478082 | 0.82 | KMT2A (0.59) | KDM4EMEN1KMT2ACYP3A4NPC1 | |
| SCHEMBL9376481 | 0.82 | KDM4E (0.51) | MAPK14KDM4ETDP1MEN1KMT2A | |
| SCHEMBL10478095 | 0.82 | RXFP1 (0.48) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9840437 | 0.81 | GAA (0.53) | MAPK14KDM4ETDP1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001986-A1 | N-(DIALKYLOXOPHOSPHINYLALKYL)-LACTAMS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-21 | — | — | WO | disclosed |