Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288549 | 0.77 | CFTR (0.50) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL21160844 | 0.76 | CTRB1 (0.45) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL30504216 | 0.75 | AKR1C1 (0.43) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL2597727 | 0.74 | CFTR (0.47) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL8076944 | 0.74 | CFTR (0.47) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL11282699 | 0.73 | CFTR (0.46) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL3505329 | 0.72 | CFTR (0.53) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL7107619 | 0.72 | CFTR (0.53) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL31084368 | 0.72 | CFTR (0.53) | CFTRGOPCGAAPKMNPSR1 | |
| SCHEMBL9787743 | 0.72 | CFTR (0.57) | CFTRGOPCGAAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112280295-A | Preparation method of high-temperature-resistant electromagnetic shielding electrical casing | 安徽实友电力金具有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-5041633-A | Process for the production of an aromatic polycarboxylic acid | AMOCO CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0375812-A1 | Process for the production of an aromatic polycarboxylic acid | AMOCO CORPORATION (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4719311-A | MULTISTAGE OXIDATION | AMOCO CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |