Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.33 |
| ▸ | CNR1 | P21554 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106248 | 0.83 | CNR2 (0.41) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL7107986 | 0.83 | CNR2 (0.41) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL7108160 | 0.83 | CNR2 (0.41) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL7112377 | 0.83 | CNR2 (0.41) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL9839650 | 0.83 | CNR2 (0.34) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL9764780 | 0.81 | CNR2 (0.34) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL27660862 | 0.77 | CYP1A2 (0.40) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL27660863 | 0.77 | CYP1A2 (0.40) | CNR2CNR1ALDH1A1TSHRMEN1 | |
| SCHEMBL6023397 | 0.73 | ALOX5 (0.47) | ALDH1A1MEN1KMT2AALOX5THRB | |
| SCHEMBL5335649 | 0.72 | ALOX5 (0.49) | ALDH1A1MEN1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | claimed |
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |