Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960398 | 0.84 | PTPN5 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL4959318 | 0.84 | PTPN5 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL201425 | 0.84 | PTPN5 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL4958978 | 0.84 | PTPN5 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL4958862 | 0.84 | PTPN5 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL4960831 | 0.82 | PTPN5 (0.44) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL11292126 | 0.81 | CEL (0.42) | PTPN5PTPN2PTGDR2CELNUDT1 | |
| SCHEMBL5887367 | 0.80 | PTGDR2 (0.41) | PTGDR2CELPTGS2CETP | |
| SCHEMBL21626185 | 0.79 | PTPN5 (0.52) | PTPN5PTPN2FEN1PTGDR2HDAC4 | |
| SCHEMBL1053897 | 0.79 | HDAC4 (0.46) | PTPN5PTPN2FEN1PTGDR2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245792-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC-ACID ESTERS | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0245792-A2 | Process for the preparation of carboxylic-acid esters | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| US-4225483-A | Boric acid esters and oxetanes for stabilizing phosphite-free polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0001823-A2 | Use of esters of boric acid to stabilize phosphite-free polycarbonates, and the obtained stabilized polycarbonate moulding compositions | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |