SCHEMBL11292126

SCHEMBL11292126

Clc1c(Sc2cccc(C3CCCCC3)c2Cl)cccc1C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CEL P19835 2/20 0.42
OPRL1 P41146 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.34
LDHA P00338 2/20 0.34
HTR1A P08908 3/20 0.33
HTR7 P34969 2/20 0.33
PTGS2 P35354 1/20 0.33
LDHB P07195 1/20 0.33
PTPN11 Q06124 1/20 0.33
GCGR P47871 1/20 0.33
PTPN5 P54829 2/20 0.32
PTPN2 P17706 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3783301 0.84 CEL (0.50) CELOPRL1PTGDR2HTR1AHTR7
SCHEMBL3792040 0.82 CEL (0.48) CELOPRL1PTGDR2HTR1AHTR7
SCHEMBL9839711 0.81 PTPN5 (0.40) CELPTGDR2HTR1AHTR7PTGS2
SCHEMBL5887367 0.80 PTGDR2 (0.41) CELPTGDR2PTGS2
SCHEMBL24069104 0.79 CEL (0.46) CELOPRL1HTR1AHTR2A
SCHEMBL126651 0.79 CEL (0.46) CELOPRL1HTR1AHTR2A
SCHEMBL3789549 0.78 CEL (0.44) CELOPRL1HTR1AHTR7PTPN5
SCHEMBL7991827 0.77 TSHR (0.45) CELOPRL1PTGDR2PTPN5PTPN2
SCHEMBL10978822 0.76 OPRL1 (0.61) CELOPRL1HTR1APTGS2
SCHEMBL3793541 0.76 CEL (0.43) CELOPRL1PTGDR2HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed