Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18157890 | 0.86 | CNR2 (0.44) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL8015431 | 0.81 | CNR2 (0.41) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL4339516 | 0.81 | CNR2 (0.44) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL9839838 | 0.81 | CNR2 (0.41) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL8027980 | 0.81 | ALDH1A1 (0.41) | CNR2ACHEEPHB4 | |
| Hydrochloric Acid SCHEMBL907030 | 0.79 | ALDH1A1 (0.43) | CNR2ACHEEPHB4 | |
| Hydrochloric Acid SCHEMBL906768 | 0.79 | ALDH1A1 (0.43) | CNR2ACHEEPHB4 | |
| Hydrochloric Acid SCHEMBL8600010 | 0.79 | CNR2 (0.43) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL19071963 | 0.78 | — | — | |
| SCHEMBL10426608 | 0.74 | CNR2 (0.37) | CNR2ACHEEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180298-B1 | PYRIMIDINE COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| EP-0134096-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-01 | — | — | EP | disclosed |
| US-4694008-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-09-15 | — | — | US | disclosed |
| EP-0180298-A2 | Pyrimidine compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-05-07 | — | — | EP | disclosed |