Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8600010 | 0.98 | CNR2 (0.43) | CNR2ACHEEPHB4NUDT1ENPP2 | |
| SCHEMBL18157890 | 0.86 | CNR2 (0.44) | CNR2ACHEEPHB4ENPP2MEN1 | |
| SCHEMBL10958555 | 0.85 | CNR2 (0.38) | CNR2ACHEEPHB4ENPP2MEN1 | |
| SCHEMBL10425952 | 0.84 | NUDT1 (0.33) | CNR2ACHENUDT1MEN1KMT2A | |
| SCHEMBL10785829 | 0.81 | HDAC1 (0.33) | CNR2NUDT1HDAC1HDAC6 | |
| SCHEMBL8027980 | 0.81 | ALDH1A1 (0.41) | CNR2ACHEEPHB4KMT2AALDH1A1 | |
| SCHEMBL9839838 | 0.81 | CNR2 (0.41) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL9839846 | 0.81 | CNR2 (0.41) | CNR2ACHEEPHB4F2RL3 | |
| SCHEMBL8015431 | 0.81 | CNR2 (0.41) | CNR2ACHEEPHB4F2RL3 | |
| Hydrochloric Acid SCHEMBL907030 | 0.79 | ALDH1A1 (0.43) | CNR2ACHEEPHB4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119549176-A | Preparation method of high-activity palladium-carbon catalyst and application of high-activity palladium-carbon catalyst in preparation of monosilane | 成都至诚大公光电科技有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-1397553-A | Process for preparing Nizatidine | BIAN LUSHENG (CN) | 2003-02-19 | — | — | CN | claimed |
| US-4904792-A | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | claimed |
| US-4348336-A | Process for the isolation of 1-naphthylamine-4,6- and 1-naphthylamine-4,7-disulphonic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | claimed |
| CN-119549176-A | Preparation method of high-activity palladium-carbon catalyst and application of high-activity palladium-carbon catalyst in preparation of monosilane | 成都至诚大公光电科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119549176-A | Preparation method of high-activity palladium-carbon catalyst and application of high-activity palladium-carbon catalyst in preparation of monosilane | 成都至诚大公光电科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-217888010-U | Equipment for synthesizing intermediate of nizatidine product | 无棣融川医药化工科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-217868685-U | Production system of nizatidine product intermediate | 无棣融川医药化工科技有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109485567-A | A kind of clean method for preparing and its intermediate of 4- hydroxymethylthiazole | 上海博璞诺科技发展有限公司 | 2019-03-19 | — | — | CN | disclosed |
| US-20090275622-A1 | NIZATIDINE FORMULATIONS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| EP-0900799-B1 | Novel atropisomers of 2,3-disubstituted-(5,6)-heteroarylfused-pyrimidin-4-ones | PFIZER PROD INC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-0968194-B1 | ATROPISOMERS OF 3-ARYL-4(3H)-QUINAZOLINONES AND THEIR USE AS AMPA-RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-4394508-A | ANTIULCER AND ANTISECRETORY AGENTS; HISTAMINE ANTAGONIST | BRISTOL-MYERS COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0083186-A2 | Thiazole derivatives as H2-receptor antagonists | ELI LILLY AND COMPANY (US) | 1983-07-06 | — | — | EP | disclosed |
| US-4382090-A | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4380639-A | ANTIULCER AND ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380638-A | ANTIULCER AND ANTISECRETORY AGENTS; DERIVATIVES OF 3-AMINO-4-HET-A | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4375547-A | ANTIHISTAMINES, 'I RECEPTOR ANTAGONISTS, ANTISECRETORY AGENTS | ELI LILLY AND COMPANY (US) | 1983-03-01 | — | — | US | disclosed |
| US-4374248-A | ANTIHISTAMINES, ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0049618-A1 | Improvements in or relating to 2,4-disubstituted thiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275622-A1 | NIZATIDINE FORMULATIONS | SLC30A5, SLC39A11, NNMT | CNR2 4039/4885ACHE 1618/4885EPHB4 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.