Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840066 | 1.00 | CHRNB2 (0.59) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL6328394 | 0.82 | GAA (0.52) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL6328393 | 0.82 | GAA (0.52) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL9839022 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL19738860 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL9839018 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL15299573 | 0.78 | LMNA (0.50) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL22090293 | 0.78 | CHRNB2 (0.57) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL22090292 | 0.78 | CHRNB2 (0.57) | CHRNB2CHRNA4GAAMAPTKMT2A | |
| SCHEMBL15286403 | 0.78 | LMNA (0.50) | CHRNB2CHRNA4GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259738-B1 | HETEROCYCLIC COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0259738-A2 | Heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-16 | — | — | EP | claimed |
| EP-0259738-B1 | HETEROCYCLIC COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4988712-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0259738-A2 | Heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-16 | — | — | EP | disclosed |