Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328271 | 0.85 | ACR (0.58) | KMT2AMEN1MAPTKDM4EACR | |
| SCHEMBL10956570 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTKDM4EF2 | |
| Hydrochloric Acid SCHEMBL7330789 | 0.84 | ACR (0.59) | KMT2AMEN1MAPTKDM4EACR | |
| SCHEMBL4066290 | 0.81 | MEN1 (0.62) | KMT2AMEN1MAPTKDM4EF2 | |
| SCHEMBL27671251 | 0.81 | PRSS1 (0.62) | PLAUKMT2AMEN1MAPTKDM4E | |
| SCHEMBL3675089 | 0.81 | KMT2A (0.69) | KMT2AMEN1MAPTKDM4EACR | |
| SCHEMBL11316711 | 0.81 | PARP10 (0.61) | PLAUPLGKMT2AMEN1F2 | |
| SCHEMBL4104661 | 0.81 | KMT2A (0.59) | PLAUKMT2AMEN1MAPTACR | |
| SCHEMBL7319794 | 0.80 | KMT2A (0.50) | PLAUPLGKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7321119 | 0.80 | PRSS1 (0.70) | KMT2AMEN1MAPTKDM4EACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077428-A | Antiinflammatory agents | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | claimed |