Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974755 | 0.87 | ALDH1A1 (0.62) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL2527782 | 0.87 | ALDH1A1 (0.62) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL2529345 | 0.87 | ALDH1A1 (0.62) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL9840100 | 0.86 | PKM (0.61) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL9840402 | 0.84 | TSHR (0.51) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL22242804 | 0.83 | TSHR (0.50) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL9839173 | 0.83 | TSHR (0.50) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL13897185 | 0.83 | TDP1 (0.71) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL17359400 | 0.83 | ALDH1A1 (0.57) | TSHRALDH1A1TP53KMT2AMAPT | |
| SCHEMBL9839050 | 0.81 | ALDH1A1 (0.63) | TSHRALDH1A1TP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002515-A1 | ANTI-INFLAMMATORY SUBSTANCES FOR COSMETIC PREPARATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-07 | — | — | WO | disclosed |