Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361775 | 0.84 | POLB (0.48) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL19369802 | 0.77 | POLB (0.53) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL9664681 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL9839006 | 0.72 | NPC1 (0.48) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10403103 | 0.70 | POLB (0.46) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10401935 | 0.69 | POLB (0.44) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10403874 | 0.69 | POLB (0.44) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10401989 | 0.68 | TSHR (0.44) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL10403223 | 0.67 | POLB (0.42) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL8042143 | 0.67 | POLB (0.42) | POLBSMN1; SMN2HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013745-A | Mercapto-1,3,4-oxadiazole or thiadiazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | claimed |
| EP-0364395-A1 | Nematicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| US-5013745-A | Mercapto-1,3,4-oxadiazole or thiadiazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0364395-A1 | Nematicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |