Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743732 | 0.87 | CTSK (0.41) | CTSK | |
| SCHEMBL9745562 | 0.86 | CTSK (0.39) | CTSKCA1CA2CA7 | |
| SCHEMBL9743070 | 0.82 | CA1 (0.37) | CTSKCA1CA2CA7 | |
| SCHEMBL9744122 | 0.80 | SMN1; SMN2 (0.39) | CTSKCA1CA2CA7 | |
| SCHEMBL10580459 | 0.74 | CA1 (0.40) | CTSKCA1CA2CA7 | |
| SCHEMBL3938694 | 0.71 | CTSK (0.38) | CTSKCA1CA2CA7 | |
| SCHEMBL3212396 | 0.70 | CTSK (0.66) | CTSKCA1CA2CA7 | |
| SCHEMBL2405499 | 0.70 | CTSK (0.66) | CTSKCA1CA2CA7 | |
| SCHEMBL9744793 | 0.69 | MEN1 (0.38) | CTSKCA1CA2CA7 | |
| SCHEMBL13596729 | 0.69 | CTSK (0.41) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051413-A | For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |