Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 12/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743070 | 0.87 | CA1 (0.37) | MEN1GAAKMT2ACTSKCA1 | |
| SCHEMBL10580459 | 0.84 | CA1 (0.40) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL9743732 | 0.82 | CTSK (0.41) | CTSK | |
| SCHEMBL24789816 | 0.77 | CA1 (0.41) | MEN1GAAKMT2ACTSKCA1 | |
| SCHEMBL9744035 | 0.76 | CA1 (0.34) | MEN1GAAKMT2ACTSKCA1 | |
| SCHEMBL9744122 | 0.74 | SMN1; SMN2 (0.39) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL17282799 | 0.72 | CA1 (0.44) | KMT2ACTSKCA1CA2CA7 | |
| SCHEMBL3409426 | 0.70 | CTSS (0.41) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL13596731 | 0.70 | CTSK (0.36) | MEN1GAAKMT2ACTSKCA1 | |
| SCHEMBL9840275 | 0.69 | CTSK (0.40) | CTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175344-A | Anticonvulsants, anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5051413-A | For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |