SCHEMBL9840324

SCHEMBL9840324

C=CCc1ccc2cc(CO)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.53
ALDH1A1 P00352 5/20 0.52
MAPT P10636 4/20 0.52
GABRA1 P14867 4/20 0.52
GABRB2 P47870 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
GAA P10253 3/20 0.52
CNR2 P34972 3/20 0.52
PPARG P37231 2/20 0.52
PPARD Q03181 2/20 0.52
CNR1 P21554 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH2 P05091 1/20 0.52
AKR1B1 P15121 1/20 0.52
HPGD P15428 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CYP3A4 P08684 4/20 0.44
ALOX5 P09917 4/20 0.44
PTGS1 P23219 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3259762 0.89 XDH (0.58) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL7043823 0.85 XDH (0.54) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL7055734 0.85 XDH (0.54) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL11494827 0.85 XDH (0.54) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL253471 0.85 XDH (0.54) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL198193 0.85 XDH (0.54) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL7555913 0.82 XDH (0.56) XDHALDH1A1MAPTGABRA1GABRB2
SCHEMBL1206769 0.82 CA2 (0.54) TSHRCYP1A2CA12CA2CA3
SCHEMBL29749150 0.82 CA2 (0.54) TSHRCYP1A2CA12CA2CA3
SCHEMBL6531216 0.82 XDH (0.57) XDHALDH1A1MAPTGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5053164-A For high speed switching MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-01 US disclosed
US-4943651-A Novel substitued naphthalene compounds and liquid crystal compositions containing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-07-24 US disclosed
EP-0332409-A2 Novel substituted naphthalene compounds and liquid crystal compositions containing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-13 EP disclosed