Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976081 | 1.00 | CES2 (0.57) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL3641573 | 1.00 | CES2 (0.57) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL8201086 | 1.00 | CES2 (0.57) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL11403890 | 0.89 | CES2 (0.64) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL1847901 | 0.86 | LMNA (0.40) | TSHR | |
| Phenol SCHEMBL7512281 | 0.85 | HSD17B3 (0.49) | CES2MEN1KMT2A | |
| SCHEMBL10797844 | 0.84 | CES2 (0.59) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL8042102 | 0.84 | CES2 (0.59) | CES2PPARGPPARDPPARAGPR84 | |
| SCHEMBL9350726 | 0.82 | CES2 (0.56) | CES2MEN1KMT2A | |
| SCHEMBL3374389 | 0.81 | HDAC1 (0.46) | CES2GPR84TSHRTDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001713-A1 | COSMETIC BASE COMPOSITION WITH THERAPEUTIC PROPERTIES | R.I.T.A. CORPORATION (US) | 1991-02-21 | — | — | WO | disclosed |
| US-4946832-A | SUCROSE FATTY ACID ESTER AND ACYL FATTY ACID ALPHA-HYDROXY CARBOXYLIC ACID | R.I.T.A. CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |