Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840520 | 0.95 | MAPT (0.50) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840561 | 0.93 | RARB (0.51) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840291 | 0.92 | RARB (0.56) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9839577 | 0.91 | RARB (0.58) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9839806 | 0.91 | RARB (0.58) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840512 | 0.91 | RARB (0.58) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840377 | 0.91 | RARB (0.58) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840224 | 0.88 | RARB (0.53) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840788 | 0.87 | RARB (0.58) | MAPTTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL9840874 | 0.86 | MAPT (0.46) | MAPTTHRBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |