Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.73 |
| ▸ | MIF | P14174 | 12/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.62 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.62 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.62 |
| ▸ | NAAA | Q02083 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332410 | 0.87 | MIF (0.79) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL9547715 | 0.85 | P2RY6 (1.00) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL1853024 | 0.85 | P2RY6 (1.00) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL10729682 | 0.82 | P2RY6 (0.70) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL8763660 | 0.81 | MIF (0.70) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL17050033 | 0.80 | MIF (0.52) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL25422578 | 0.79 | P2RY6 (0.66) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL347652 | 0.79 | P2RY6 (0.79) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL13623261 | 0.79 | P2RY6 (0.65) | P2RY6MIFTRPA1CYP2E1CYP2A6 | |
| SCHEMBL2947970 | 0.78 | MIF (1.00) | MIFTRPA1CYP2E1CYP2A6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011861-A | Containing functional groups capable of bonding peptides and proteins | MILLIPORE CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0353460-A2 | Membranes for solid phase protein sequencing | MILLIPORE CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |