Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640291 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL43909 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL28175178 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTCA12CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL9517245 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL1759364 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTCA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL421277 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTCA12CA2CA9 | |
| Sodium Chloride SCHEMBL421276 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTCA12CA2CA9 | |
| Diphenylamine SCHEMBL1961990 | 0.77 | HSD17B10 (0.67) | ALDH1A1MAPTHSD17B10L3MBTL1CYP1A2 | |
| SCHEMBL302557 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL2782722 | 0.73 | MAPT (0.58) | ALDH1A1MAPTHSD17B10L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001983-A1 | CYCLOBUTARENE KETOANHYDRIDE AND KETOCARBOXY MONOMERIC AND POLYMERIC COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |
| EP-0410039-A1 | Cyclobutarene ketoanhydride and ketocarboxy monomeric and polymeric compositions | THE DOW CHEMICAL COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |