Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952189 | 0.82 | PGR (0.51) | ALDH1A1TSHRHTT | |
| SCHEMBL10997472 | 0.79 | GRM5 (0.53) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL7746719 | 0.78 | MAPT (0.58) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL6699454 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL5914229 | 0.76 | RPS6KA2 (0.42) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10696845 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTTSHRLMNACYP3A4 | |
| SCHEMBL7439011 | 0.76 | MEN1 (0.43) | ALDH1A1MAPTCA2TSHRMEN1 | |
| SCHEMBL4960970 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL11770442 | 0.76 | MAPT (0.41) | ALDH1A1MAPTCA12CA2CA9 | |
| SCHEMBL7742450 | 0.76 | ERCC1 (0.51) | ALDH1A1MAPTCA12CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139493-A1 | PREPARATION OF VELPATASVIR AND DERIVATIVE THEREOF | SHANGHAI FOREFRONT PHARMACEUTICAL CO LTD (CN) | 2021-05-13 | — | — | US | claimed |
| CN-106831737-B | Preparation of vipatavir and derivatives thereof | 上海众强药业有限公司 | 2020-03-17 | — | — | CN | claimed |
| EP-2681224-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-01-08 | — | — | EP | claimed |
| CN-102015993-B | Encapsulated benefit agent | UNILEVER PLC | 2013-03-27 | — | — | CN | claimed |
| WO-2012117038-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-09-07 | — | — | WO | claimed |
| EP-0920527-B1 | SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE | BRISTOL MYERS SQUIBB CO (US) | 2008-03-19 | — | — | EP | claimed |
| EP-1004580-B1 | Imides as inhibitors of TNF alpha | CELGENE CORP (US) | 2006-12-20 | — | — | EP | claimed |
| CN-1268636-C | Dolastatin 15 derivatives | ABSF AG (DE) | 2006-08-09 | — | — | CN | claimed |
| EP-1232183-B1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2006-01-18 | — | — | EP | claimed |
| US-20050239841-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| EP-0000931-A1 | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO. INC. (US) | 1979-03-07 | — | — | EP | claimed |
| US-4093625-A | 6-Sulfur analogs of penicillins and cephalosporins | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1978-06-06 | — | — | US | claimed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | claimed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | claimed |
| US-4016042-A | SYNTHETIC OLIGOPEPTIDE CONTAINING A CHROMOGENIC OR FLUORESCENT GROUP SPLIT OFF BY PROTEOLYTIC ENZYMES | PENTAPHARM A.G. (CH) | 1977-04-05 | — | — | US | claimed |
| US-4014874-A | Process for the manufacture of 3-substituted thiomethyl-7-amino-2-cephem-4-carboxylic acid compound | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3984401-A | Process for producing lactol-type cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | claimed |
| US-3965098-A | Intermediates for preparing cephalosporins and methods of production | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139493-A1 | PREPARATION OF VELPATASVIR AND DERIVATIVE THEREOF | SAMHD1, TYMP, PNP | ALDH1A1 393/4885MAPT 1583/4885CA12 4642/4885 |
| US-20050239841-A1 | New compounds | MCHR1, NPY1R, HCRTR1 | ALDH1A1 1918/4885MAPT 665/4885CA12 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.