Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212391 | 0.85 | PDCD1 (0.47) | ELANEPDCD1CD274CALM1CTRC | |
| SCHEMBL8098213 | 0.78 | CALM1 (0.55) | CALM1CTRCBCL2BCL2L1ALOX5 | |
| SCHEMBL9181341 | 0.78 | CD274 (0.67) | PDCD1CD274NPC1HPGDRAB9A | |
| SCHEMBL7863116 | 0.77 | PTPN1 (0.50) | — | |
| SCHEMBL10905320 | 0.76 | ELANE (0.53) | ELANEBCL2BCL2L1CTSGALOX5 | |
| SCHEMBL10484543 | 0.76 | PDCD1 (0.47) | PDCD1CD274NPC1HPGDBCL2L1 | |
| SCHEMBL2488776 | 0.75 | CD274 (0.39) | PDCD1CD274SMN1; SMN2 | |
| SCHEMBL27773385 | 0.73 | ELANE (0.37) | ELANEBCL2BCL2L1CTSGCYP11B1 | |
| SCHEMBL11207724 | 0.73 | PTGS1 (0.42) | PDCD1CD274CALM1BCL2BCL2L1 | |
| SCHEMBL4473038 | 0.72 | TDP2 (0.46) | PDCD1CD274ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | disclosed |