Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | GABRE | P78334 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840536 | 0.90 | GABRA1 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9840559 | 0.86 | GABRA1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10374401 | 0.84 | GABRA1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9838989 | 0.82 | GABRA1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9840083 | 0.80 | GABRA1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10376245 | 0.80 | GABRA1 (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10376611 | 0.79 | GABRA1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10375636 | 0.79 | GABRA1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10729199 | 0.78 | GABRA1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10417016 | 0.78 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222693-B1 | 3-OXADIAZOLYL AND 3-CARBOXYLIC-ACID BETA-CARBOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-17 | — | — | EP | disclosed |
| US-4778800-A | ANXIOLYTIC, ANTICONVULSANT | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |