Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446029 | 0.90 | CTSL (0.49) | TGM2CTSLRAB9A | |
| SCHEMBL11351133 | 0.90 | CTSL (0.49) | TGM2CTSLRAB9A | |
| SCHEMBL14050011 | 0.82 | HDAC1 (0.55) | TGM2CTSLRAB9A | |
| SCHEMBL7417267 | 0.81 | PPARG (0.52) | GAAALDH1A1HTR2AMAPTRAB9A | |
| SCHEMBL31151026 | 0.81 | CASP1 (0.52) | CTSL | |
| SCHEMBL11813273 | 0.80 | ATM (0.60) | ALDH1A1ATMCTSL | |
| SCHEMBL10898520 | 0.80 | CTSL (0.49) | TGM2CTSL | |
| SCHEMBL11709602 | 0.80 | CTSL (0.49) | HTR2ATGM2CTSL | |
| SCHEMBL11867075 | 0.80 | CTSL (0.49) | TGM2CTSL | |
| SCHEMBL11867081 | 0.80 | CTSL (0.49) | TGM2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990614-A | N-heterocyclic amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4918107-A | HYDROXYPHENYLACETYL-L-ASPARAGINYL COMPOUNDS | TSUMURA & CO. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0311517-A2 | Amide compound having glutamate receptor inhibiting activity | Takeda Chemical Industries, Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |