Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840575 | 0.90 | HRH2 (0.51) | BCHEACHEHRH2HRH1KMT2A | |
| SCHEMBL15809950 | 0.86 | KMT2A (0.62) | HRH2HRH1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1361202 | 0.86 | KMT2A (0.62) | HRH2HRH1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9840764 | 0.86 | TGM2 (0.47) | KMT2AMAPK1P2RY12 | |
| SCHEMBL5064576 | 0.82 | HRH2 (0.58) | HRH2HRH1KMT2AMAPK1CYP3A4 | |
| SCHEMBL15810045 | 0.82 | HRH2 (0.58) | HRH2HRH1KMT2AMAPK1CYP3A4 | |
| SCHEMBL15810046 | 0.82 | HRH2 (0.58) | HRH2HRH1KMT2AMAPK1CYP3A4 | |
| SCHEMBL9840610 | 0.81 | TSHR (0.44) | HRH2HRH1KMT2AITGB3ITGA2B | |
| SCHEMBL15809918 | 0.80 | HRH2 (0.55) | HRH2HRH1KMT2AMAPK1CYP3A4 | |
| SCHEMBL15809917 | 0.80 | HRH2 (0.55) | HRH2HRH1KMT2AMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990614-A | N-heterocyclic amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0311517-A2 | Amide compound having glutamate receptor inhibiting activity | Takeda Chemical Industries, Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |