Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840713 | 0.89 | KMT2A (0.47) | TGM2P2RY12KMT2AMC4RMAPK1 | |
| SCHEMBL9840695 | 0.86 | BCHE (0.51) | P2RY12KMT2AMAPK1 | |
| SCHEMBL14850779 | 0.84 | KMT2A (0.48) | TGM2KMT2AMC4RMAPK1POLB | |
| SCHEMBL6982783 | 0.84 | MAPK1 (0.61) | KMT2AMC4RMAPK1POLBGFER | |
| SCHEMBL9840610 | 0.82 | TSHR (0.44) | TGM2P2RY12KMT2A | |
| SCHEMBL9483838 | 0.80 | KMT2A (0.56) | KMT2AMC4RMAPK1POLBGFER | |
| SCHEMBL9483845 | 0.80 | KMT2A (0.56) | KMT2AMC4RMAPK1POLBGFER | |
| SCHEMBL9840492 | 0.80 | TSHR (0.42) | TGM2P2RY12KMT2A | |
| SCHEMBL4510471 | 0.80 | MC4R (0.56) | KMT2AMC4RMAPK1POLBGFER | |
| SCHEMBL2585308 | 0.79 | P2RY12 (0.50) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990614-A | N-heterocyclic amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0311517-A2 | Amide compound having glutamate receptor inhibiting activity | Takeda Chemical Industries, Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |