SCHEMBL9840761

SCHEMBL9840761

[NH]S(=O)(=O)c1c(N)ccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
HSD17B10 Q99714 4/20 0.43
TSHR P16473 2/20 0.43
HPGD P15428 2/20 0.43
KEAP1 Q14145 2/20 0.43
CYP3A4 P08684 1/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
HPRT1 P00492 2/20 0.41
CA9 Q16790 2/20 0.41
CYP2A6 P11509 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTR6 P50406 1/20 0.39
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
PAX8 Q06710 1/20 0.36
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35
SUMO2 P61956 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2539474 0.82 CA1 (0.52) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL313224 0.81 CYP2D6 (0.46) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL10904716 0.81 HPRT1 (0.46) ALDH1A1HSD17B10TSHRHPGDKEAP1
Potassium Ion SCHEMBL5696234 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL5696256 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRHPGDKEAP1
Ammonia Solution, Strong SCHEMBL5696243 0.79 CYP2D6 (0.45) ALDH1A1HSD17B10TSHRHPGDKEAP1
Ammonia Solution, Strong SCHEMBL5696244 0.79 CYP2D6 (0.45) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL5696257 0.79 CYP2D6 (0.45) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL8610190 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL5696235 0.79 CYP2D6 (0.45) ALDH1A1HSD17B10TSHRHPGDKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996296-A Cromolyn binding protein in highly purifed form, and methods for the isolation thereof YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1991-02-26 US disclosed