Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840761 | 0.82 | ALDH1A1 (0.43) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL8416358 | 0.82 | CYP2A6 (0.50) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL10904716 | 0.82 | HPRT1 (0.46) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL313224 | 0.82 | CYP2D6 (0.46) | CA1CA9CA2PKMRAB9A | |
| Ammonia Solution, Strong SCHEMBL5696244 | 0.81 | CYP2D6 (0.45) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL5696256 | 0.81 | ALDH1A1 (0.42) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL8610190 | 0.81 | ALDH1A1 (0.42) | CA1CA9CA2PKMRAB9A | |
| Ammonia Solution, Strong SCHEMBL5696243 | 0.81 | CYP2D6 (0.45) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL5696257 | 0.81 | CYP2D6 (0.45) | CA1CA9CA2PKMRAB9A | |
| SCHEMBL5696235 | 0.81 | CYP2D6 (0.45) | CA1CA9CA2PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55110937-A | — | — | None | — | — | JP | disclosed |
| JP-55110938-A | — | — | None | — | — | JP | disclosed |
| EP-2970141-A2 | HALOGENOPYRAZOLES AS INHIBITORS OF THROMBIN | Verseon Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149139-A2 | HALOGENOPYRAZOLES AS INHIBITORS OF THROMBIN | VERSEON, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-8044101-B2 | Nitrosation-inducible inhibitors biological macromolecules | NEW YORK UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-20090325203-A1 | Assay For Tissue Factor And Factor Vlla | JENNY RICHARD J | 2009-12-31 | — | — | US | disclosed |
| US-7604932-B2 | And blood-coagulation factor VII using aminonapthalene sulfonamide-based fluorogenic substrates | HAEMATOLOGIC TECHNOLOGIES, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NEW YORK UNIVERSITY (US) | 2009-07-23 | — | — | US | disclosed |
| US-7511076-B2 | Deactivated proteins | NEW YORK UNIVERSITY (US) | 2009-03-31 | — | — | US | disclosed |
| US-20060148022-A1 | Assay for tissue factor and factor VIIa | HAEMATOLOGIC TECHNOLOGIES, INC | 2006-07-06 | — | — | US | disclosed |
| EP-1007078-A1 | PEPTIDOMIMETICS CONTAINING 6-PEPTIDYLAMINO-1-NAPHTHALENESULFONAMIDE MOIETIES | Butenas, Saulius (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999064622-A1 | INHIBITION OF COAGULATION IN BLOOD AND BLOOD PRODUCTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998022125-A9 | PEPTIDOMIMETICS CONTAINING 6-PEPTIDYLAMINO-1-NAPHTHALENESULFONAMIDE MOIETIES | — | 1998-10-08 | — | — | WO | disclosed |
| WO-1998022125-A1 | PEPTIDOMIMETICS CONTAINING 6-PEPTIDYLAMINO-1-NAPHTHALENESULFONAMIDE MOIETIES | BUTENAS SAULIUS (US) | 1998-05-28 | — | — | WO | disclosed |
| US-4906740-A | Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4906740-A | Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| JP-S55110938-A | METHOD OF FLUOROMETRIC DETERMINATION OF GLUTATHIONE | YUKI GOSEI YAKUHIN KOGYO KK | 1980-08-27 | — | — | JP | disclosed |
| JP-S55110937-A | METHOD OF FLUOMETRIC QUANTATIVE ANALYSIS OF AMINO ACID, PEPTIDE OR PROTEIN USING SODIUM N-CHLORO-1- DIMETHYLAMINONAPHTHALENE-5-SULFONAMIDE | YUKI GOSEI YAKUHIN KOGYO KK | 1980-08-27 | — | — | JP | disclosed |
| US-4125368-A | Metallized monoazo dyes | TOMS RIVER CHEMICAL CORP. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4058515-A | Metallized phenyl-azo-naphthol compounds | TOMS RIVER CHEMICAL CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NOS2, NOS1, NOS3 | CA1 3705/4885CA9 3946/4885CA2 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.