Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964299 | 0.89 | KDM4E (0.57) | KDM4ETDP1ALDH1A1GAAHPGD | |
| SCHEMBL30602834 | 0.89 | KDM4E (0.57) | KDM4ETDP1ALDH1A1GAAHPGD | |
| SCHEMBL18229465 | 0.85 | OXER1 (0.64) | KDM4ETDP1ALDH1A1GAAHPGD | |
| SCHEMBL27637619 | 0.81 | KDM4E (0.49) | KDM4ETDP1HTTPBRM1ALDH1A1 | |
| SCHEMBL1538815 | 0.79 | ALDH1A1 (0.50) | KDM4ETDP1ALDH1A1LMNARAB9A | |
| SCHEMBL26963262 | 0.79 | KDM4E (0.55) | KDM4ETDP1HTTALDH1A1LMNA | |
| SCHEMBL10481531 | 0.79 | HTT (0.54) | KDM4ETDP1HTTALDH1A1GAA | |
| SCHEMBL10513594 | 0.79 | RAB9A (0.65) | KDM4ETDP1HTTPBRM1ALDH1A1 | |
| SCHEMBL6280799 | 0.77 | KDM4E (0.59) | KDM4ETDP1HTTPBRM1ALDH1A1 | |
| SCHEMBL20274465 | 0.77 | HTT (0.60) | KDM4EHTTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |