SCHEMBL9841149

SCHEMBL9841149

[N-]=[N+]=NOc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
CA4 P22748 1/20 0.36
SRC P12931 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNA3 P22001 1/20 0.33
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOA P21397 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RECQL P46063 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16350499 0.74
SCHEMBL824571 0.72 LTA4H (0.32) LTA4HTSHRCA4
SCHEMBL17689257 0.72 ESR2 (0.47) LTA4HNR1H2BAX
SCHEMBL29112207 0.72 HPGD (0.37) TSHRALDH1A1
SCHEMBL16353372 0.72 FURIN (0.32)
SCHEMBL26686884 0.70
SCHEMBL25426237 0.69 SRC (0.48) TSHRSRCTDP1L3MBTL1CYP2C9
SCHEMBL29096159 0.69 CA4 (0.32) LTA4HTSHRCA4
SCHEMBL98878 0.69 SRC (0.48) TSHRSRCTDP1L3MBTL1CYP2C9
SCHEMBL16350501 0.69 GRIN2D (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271249-A Diazonium transfer reagent and preparation method and application thereof 中国科学院上海有机化学研究所 2024-07-02 CN disclosed
EP-3483193-B1 CURABLE COMPOSITION, METHOD FOR PRODUCING SAME, AND ARTICLE PRODUCED THEREWITH DAIKIN IND LTD (JP) 2023-08-23 EP disclosed
US-20100173871-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-08 US disclosed
CN-1166729-C Cross-linking of polymers and foams thereof 2004-09-15 CN disclosed
CN-1098287-C Thermoset interpolymers and foams DOW CHEMICAL CO (US) 2003-01-08 CN disclosed
CN-1276801-A Thermoset interpolymers and foams DOW CHEMICAL CO (US) 2000-12-13 CN disclosed
CN-1275996-A Process for coupling alpha-olefin/vinyl aromatic monomer or hindered aliphatic vinyl monomer interpolymers with polyolefin blends DOW CHEMIAL CO (US) 2000-12-06 CN disclosed
CN-1270609-A Cross-linking of polymers and foams thereof DOW CHEMICAL CO (US) 2000-10-18 CN disclosed
US-5039814-A Chemical intermediates for angiotensin antagonist MERCK & CO., INC. (US) 1991-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173871-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CD14, DUSP3, IRAK3 LTA4H 1363/4885TSHR 4090/4885CA4 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.