Dymanthine

Dymanthine

SCHEMBL9841230

CCCCCCCCCCCCCCCCCCN(C)C.CCCCCCCCCCCCc1ccccc1S(=O)(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
HTR6 P50406 2/20 0.42
DNM1 Q05193 3/20 0.42
THRA P10827 3/20 0.41
THRB P10828 3/20 0.41
METAP2 P50579 1/20 0.40
NPY2R P49146 1/20 0.40
BID P55957 2/20 0.40
BCL2L1 Q07817 2/20 0.40
MCL1 Q07820 2/20 0.40
BAK1 Q16611 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30935366 0.92 LIPG (0.41) LIPGSIGMAR1HTR6THRATHRB
SCHEMBL18262976 0.92 LIPG (0.41) LIPGSIGMAR1HTR6THRATHRB
Dimethylaminoethanol SCHEMBL2276031 0.92 LIPG (0.43) LIPGHTR6THRATHRBBID
SCHEMBL5461960 0.92 SIGMAR1 (0.47) LIPGSIGMAR1THRATHRBMETAP2
SCHEMBL10930852 0.90 KCNH2 (0.47) LIPGTHRATHRBMETAP2BID
SCHEMBL6471485 0.90 LIPG (0.54) LIPGTHRATHRBBIDBCL2L1
Nonane SCHEMBL5533194 0.90 LIPG (0.54) LIPGTHRATHRBBIDBCL2L1
SCHEMBL150981 0.90 LIPG (0.54) LIPGTHRATHRBBIDBCL2L1
SCHEMBL21121138 0.90 LIPG (0.54) LIPGTHRATHRBBIDBCL2L1
SCHEMBL153186 0.90 LIPG (0.54) LIPGTHRATHRBBIDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3064368-A None JP disclosed
JP-H0364368-A ANTISTATIC AGENT AND RESIN COMPOSITION SANYO CHEM IND LTD 1991-03-19 JP disclosed