⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855446 | 0.85 | OXER1 (0.30) | — | |
| SCHEMBL6605454 | 0.82 | — | — | |
| SCHEMBL18300093 | 0.82 | — | — | |
| SCHEMBL8441630 | 0.76 | — | — | |
| SCHEMBL15869646 | 0.76 | OXER1 (0.30) | — | |
| SCHEMBL9405218 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL10447727 | 0.72 | FAAH (0.41) | — | |
| SCHEMBL3266583 | 0.72 | TSHR (0.42) | — | |
| SCHEMBL11257904 | 0.72 | TSHR (0.42) | — | |
| SCHEMBL11250666 | 0.72 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073607-A | POLYIMIDE COMPOSITIONS CONTAINING POLYORGANOSILOXANE FOR IMPROVING ATOMIC OXYGEN RESISTANCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0417778-A1 | Polyimide compositions containing polyorganosiloxane for improving atomic oxygen resistance | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |