Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | RXRB | P28702 | 1/20 | 0.57 |
| ▸ | SOD1 | P00441 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841601 | 0.89 | NQO1 (0.54) | RXRARXRBAPPTDP1L3MBTL1 | |
| Fluoride SCHEMBL9841619 | 0.85 | APP (0.49) | APPSMN1; SMN2 | |
| Fluoride SCHEMBL9841526 | 0.85 | HRH3 (0.48) | APPHRH3MAOB | |
| Fluoride SCHEMBL9841316 | 0.85 | APP (0.49) | APPL3MBTL1HRH3 | |
| Fluoride SCHEMBL9841773 | 0.82 | HRH3 (0.52) | HRH3KMT2AMEN1SMN1; SMN2 | |
| Fluoride SCHEMBL9841299 | 0.82 | NR5A1 (0.54) | APPHRH3NPC1RAB9A | |
| Fluoride SCHEMBL9841357 | 0.81 | HRH3 (0.58) | L3MBTL1HRH3RAB9AKMT2AMEN1 | |
| Fluoride SCHEMBL9841296 | 0.81 | NR5A1 (0.57) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| Fluoride SCHEMBL9841761 | 0.81 | NR5A1 (0.57) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| Fluoride SCHEMBL3782861 | 0.81 | TP53 (0.48) | TDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |