Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841773 | 0.90 | HRH3 (0.52) | HRH3BCHELTA4HEPHX2 | |
| SCHEMBL16440937 | 0.89 | APP (0.56) | HRH3APPSENP8SENP7SENP6 | |
| Fluoride SCHEMBL9841357 | 0.88 | HRH3 (0.58) | HRH3BCHELTA4HEPHX2 | |
| Fluoride SCHEMBL9841709 | 0.87 | HRH3 (0.57) | HRH3BCHELTA4HEPHX2 | |
| Fluoride SCHEMBL9841864 | 0.87 | HRH3 (0.57) | HRH3BCHELTA4HEPHX2 | |
| Fluoride SCHEMBL9841505 | 0.87 | HRH3 (0.57) | HRH3BCHELTA4HEPHX2 | |
| Fluoride SCHEMBL9841619 | 0.86 | APP (0.49) | APPLTA4H | |
| Fluoride SCHEMBL9841316 | 0.86 | APP (0.49) | HRH3APPLTA4H | |
| Fluoride SCHEMBL9841293 | 0.85 | RXRA (0.57) | HRH3APPMAOB | |
| Fluoride SCHEMBL9841601 | 0.85 | NQO1 (0.54) | GPR84APPMAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |