SCHEMBL9841553

SCHEMBL9841553

CCCCCCCOC12CCC(c3ccc(S(F)(F)(F)(F)F)cc3)(CC1)CC2

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NR5A1 Q13285 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9841587 1.00 KDM1A (0.33) KDM1ACYP2C9CYP2C19MEN1RECQL
SCHEMBL9841861 1.00 KDM1A (0.33) KDM1ACYP2C9CYP2C19MEN1RECQL
SCHEMBL9841410 0.99 KDM1A (0.33) KDM1AMEN1KMT2A
SCHEMBL9841692 0.94 KDM1A (0.34) KDM1AMEN1KMT2A
SCHEMBL9842082 0.83 KDM1A (0.38) KDM1A
Fluoride SCHEMBL9841550 0.81 MEN1 (0.33) CYP2C9CYP2C19MEN1RECQLKMT2A
Fluoride SCHEMBL9841583 0.81 MEN1 (0.33) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL9841595 0.79 HSD11B1 (0.37) KDM1A
SCHEMBL9841191 0.71 KDM1A (0.41) KDM1A
SCHEMBL1291918 0.70 NR5A1 (0.59) NR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed